The veterinary tranquilizer xylazine is indispensable in large-animal care, and some veterinarians worry that listing xylazine as a controlled substance to make distribution for human use illegal would require veterinarians to maintain logbooks and manufacturers to implement controls that might raise the drug’s price or discourage them from making the drug altogether. Instead of listing xylazine as a controlled substance, a proposed bill in the House and Senate would make it illegal to sell or distribute xylazine for human use, and it has been endorsed by veterinary, ranching and law enforcement organizations.